IGF 1 LR3 1mg is formulated for precise research applications. At Ultra Peps, we prioritize consistency, reliability, and research-focused handling standards.
Insulin-like growth factor pathway studies
Cellular proliferation, differentiation, and growth factor-mediated signaling
Trusted research supplier
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IGF-1 LR3 1mg (Long Arginine 3-IGF-1) is a synthetic analog of insulin-like growth factor-1 commonly studied for its interaction with cellular growth pathways, nutrient signaling, and anabolic research models. Additionally, researchers continue investigating IGF-1 LR3 because of its extended activity profile and influence on cellular development mechanisms.
Its modified structure and prolonged activity have made IGF-1 LR3 a widely recognized compound in advanced peptide and metabolic research environments. Furthermore, researchers frequently utilize this analog in studies involving cellular communication, growth factor regulation, receptor activation, and molecular signaling networks. As a result, IGF-1 LR3 remains a valuable tool for investigating long-duration growth factor signaling and receptor-mediated biological activity.
Mode of Action
IGF-1 LR3 is a modified analog of insulin-like growth factor-1 containing an arginine substitution at position three and an additional thirteen amino acids attached to the N-terminal region. These structural modifications significantly reduce binding to insulin-like growth factor-binding proteins (IGFBPs). This allows a greater proportion of the peptide to remain biologically available for receptor interaction.
As a result, IGF-1 LR3 exhibits a longer duration of activity and prolonged receptor engagement compared to native IGF-1.
Furthermore, IGF-1 LR3 binds to insulin-like growth factor-1 receptors (IGF-1R) located on the surface of target cells, activating intracellular signaling pathways including PI3K/Akt and MAPK/ERK. Consequently, these signaling cascades regulate gene transcription, protein synthesis, cellular proliferation, differentiation, and metabolic communication processes. Because receptor activation persists for a longer period due to reduced binding protein interactions, IGF-1 LR3 is frequently utilized to investigate extended growth factor signaling and downstream cellular responses.
Lastly, it possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1’s half-life of about 12–15 hours).
Research Applications
Researchers continue evaluating IGF-1 LR3 across several scientific disciplines involving growth signaling and metabolic regulation.
Common Research Areas Include:
Insulin-like growth factor pathway studies
Cellular growth and proliferation investigations
Anabolic signaling research
Nutrient utilization and metabolism models
Muscle-cell activity and protein synthesis studies
Recovery and tissue-support investigations
Endocrine and cellular communication research
Ongoing scientific interest continues surrounding IGF-1 LR3 due to its potential role in growth-related signaling and regenerative pathway activity.
IGF-1 DES is the closest structural relative to IGF-1 LR3. Both peptides belong to the insulin-like growth factor family and are frequently studied for their interaction with IGF-1 receptors and growth factor signaling pathways. Researchers often compare the two compounds to evaluate differences in activity duration, receptor engagement, and localized signaling characteristics.
IGF-2 is another member of the insulin-like growth factor family and is commonly investigated for its role in cellular communication, growth factor signaling, and developmental biology. Researchers frequently study IGF-1 LR3 and IGF-2 together to better understand similarities and differences in receptor interactions and signaling activity.
Researchers often examine CJC-1295 No DAC and Ipamorelin in studies involving growth hormone signaling and downstream IGF-related pathways. These compounds provide useful comparative models for investigating the relationship between endocrine communication and growth factor regulation.
These growth hormone secretagogues are frequently studied alongside IGF-1 LR3 to explore how different signaling pathways influence growth factor activity, receptor communication, and endocrine regulation.
Tesamorelin is a GHRH analog commonly utilized in endocrine signaling research involving growth hormone and IGF-related pathways. Researchers often compare its signaling profile with IGF-focused compounds to better understand pathway interactions.
PEG-MGF is frequently studied in conjunction with IGF-related peptides due to its relationship with growth factor signaling and cellular communication pathways. Researchers often investigate both compounds in studies involving molecular regulation and peptide pharmacology.
Follistatin 344 is commonly examined in research involving growth-regulating proteins, myostatin signaling, and cellular regulation. Researchers sometimes compare follistatin-related pathways with IGF-related signaling networks to better understand biological regulation mechanisms.
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Peptides should be stored properly to maintain their stability and effectiveness. Here are some general guidelines for storing peptides:
1. Lyophilized (Dry/Powder) Peptides:
Storage Temperature: Store at -20°C or -80°C. Lyophilized peptides are typically more stable at lower temperatures.
Avoid Moisture: Keep them in airtight containers to avoid moisture exposure, which can degrade peptides.
Expiration: Lyophilized peptides generally have a longer shelf life when stored properly (up to a year or more).
2. Reconstituted Peptides (in Solution):
Storage Temperature: If you’ve dissolved a peptide in a solvent (e.g., water, acetic acid, or another buffer), you should store it at 2–8°C (36–46°F)
Protect from Light: Peptides in solution can degrade when exposed to light, so store them in amber-colored vials or protect them from light using foil or opaque containers.
Stability: Once reconstituted, peptides are typically stable for a few days to a few weeks at 4°C, depending on the sequence and conditions, but freezing is often the safest option for long-term storage.
3. Special Considerations:
Buffer Choice: Ensure the peptide is dissolved in an appropriate buffer to maintain stability. Some peptides may degrade in certain solvents, so it’s essential to choose the right one.
Avoid Contamination: Always handle peptides with clean equipment (e.g., sterile vials, pipettes) to prevent contamination that could affect their stability.
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Each unit is prepared with attention to consistency. Packaging is sealed and reinforced to protect shipment integrity. In addition, we offer Protection Coverage at checkout as an additional option which covers lost or damaged packages ($3.99). We’ll re-ship or refund eligible orders once confirmed. For additional information please visit our Shipping Policy and tracking Info Page
We ship USPS Priority only
Ships same day M-F (before 4pm est cutoff)
Orders placed on a Federal holiday or weekend will be delivered on the next business day
Free shipping on orders over $150. This offer will be available based on post-discount order amount
Signature confirmation is offered at checkout for $19.99
Yes, we ship to PO Boxes
Tracking & Insurance (up to $100 via USPS) is included
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
I. RESEARCH USE ONLY: Products are sold strictly for laboratory research and in-vitro testing, not for human or animal use. II. ASSUMPTION OF RISK: You assume all risk associated with these chemicals. III. LIABILITY: You agree to indemnify BCUltra LLC for any misuse, including human consumption. IV. COMPLIANCE: You certify you are 21+ & will handle these peptides & chems per all applicable law.
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IGF 1 LR3 1mg
$55.99 – $245.99Price range: $55.99 through $245.99
IGF 1 LR3 1mg is formulated for precise research applications. At Ultra Peps, we prioritize consistency, reliability, and research-focused handling standards.
Description
IGF-1 LR3 1mg (Long Arginine 3-IGF-1) is a synthetic analog of insulin-like growth factor-1 commonly studied for its interaction with cellular growth pathways, nutrient signaling, and anabolic research models. Additionally, researchers continue investigating IGF-1 LR3 because of its extended activity profile and influence on cellular development mechanisms.
Its modified structure and prolonged activity have made IGF-1 LR3 a widely recognized compound in advanced peptide and metabolic research environments. Furthermore, researchers frequently utilize this analog in studies involving cellular communication, growth factor regulation, receptor activation, and molecular signaling networks. As a result, IGF-1 LR3 remains a valuable tool for investigating long-duration growth factor signaling and receptor-mediated biological activity.
Mode of Action
IGF-1 LR3 is a modified analog of insulin-like growth factor-1 containing an arginine substitution at position three and an additional thirteen amino acids attached to the N-terminal region. These structural modifications significantly reduce binding to insulin-like growth factor-binding proteins (IGFBPs). This allows a greater proportion of the peptide to remain biologically available for receptor interaction.
As a result, IGF-1 LR3 exhibits a longer duration of activity and prolonged receptor engagement compared to native IGF-1.
Furthermore, IGF-1 LR3 binds to insulin-like growth factor-1 receptors (IGF-1R) located on the surface of target cells, activating intracellular signaling pathways including PI3K/Akt and MAPK/ERK. Consequently, these signaling cascades regulate gene transcription, protein synthesis, cellular proliferation, differentiation, and metabolic communication processes. Because receptor activation persists for a longer period due to reduced binding protein interactions, IGF-1 LR3 is frequently utilized to investigate extended growth factor signaling and downstream cellular responses.
Lastly, it possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1’s half-life of about 12–15 hours).
Research Applications
Researchers continue evaluating IGF-1 LR3 across several scientific disciplines involving growth signaling and metabolic regulation.
Common Research Areas Include:
Ongoing scientific interest continues surrounding IGF-1 LR3 due to its potential role in growth-related signaling and regenerative pathway activity.
Related Research Compounds
IGF-1 DES
IGF-1 DES is the closest structural relative to IGF-1 LR3. Both peptides belong to the insulin-like growth factor family and are frequently studied for their interaction with IGF-1 receptors and growth factor signaling pathways. Researchers often compare the two compounds to evaluate differences in activity duration, receptor engagement, and localized signaling characteristics.
IGF-2
IGF-2 is another member of the insulin-like growth factor family and is commonly investigated for its role in cellular communication, growth factor signaling, and developmental biology. Researchers frequently study IGF-1 LR3 and IGF-2 together to better understand similarities and differences in receptor interactions and signaling activity.
CJC-1295 No DAC & Ipam
Researchers often examine CJC-1295 No DAC and Ipamorelin in studies involving growth hormone signaling and downstream IGF-related pathways. These compounds provide useful comparative models for investigating the relationship between endocrine communication and growth factor regulation.
GHRP-2, GHRP-6, and Hexarelin
These growth hormone secretagogues are frequently studied alongside IGF-1 LR3 to explore how different signaling pathways influence growth factor activity, receptor communication, and endocrine regulation.
Tesamorelin
Tesamorelin is a GHRH analog commonly utilized in endocrine signaling research involving growth hormone and IGF-related pathways. Researchers often compare its signaling profile with IGF-focused compounds to better understand pathway interactions.
PEG-MGF
PEG-MGF is frequently studied in conjunction with IGF-related peptides due to its relationship with growth factor signaling and cellular communication pathways. Researchers often investigate both compounds in studies involving molecular regulation and peptide pharmacology.
Follistatin 344
Follistatin 344 is commonly examined in research involving growth-regulating proteins, myostatin signaling, and cellular regulation. Researchers sometimes compare follistatin-related pathways with IGF-related signaling networks to better understand biological regulation mechanisms.
Selected Literature
Read our Blog: What Is IGF-1 LR3? A Guide for Biological Researchers
Read our Blog: What Peptides Do in the Body: Understanding Their Role in Biological Research
Read our Blog: Understanding Peptide Half-Life in Research: Stability, Signaling, and Duration
Chemical Details
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Additional information
Solid (Powder)
White
1mg
Hormone
Research Peptide
Ultra Peps
1, 5
Peptides should be stored properly to maintain their stability and effectiveness. Here are some general guidelines for storing peptides:
1. Lyophilized (Dry/Powder) Peptides:
Storage Temperature: Store at -20°C or -80°C. Lyophilized peptides are typically more stable at lower temperatures.
Avoid Moisture: Keep them in airtight containers to avoid moisture exposure, which can degrade peptides.
Expiration: Lyophilized peptides generally have a longer shelf life when stored properly (up to a year or more).
2. Reconstituted Peptides (in Solution):
Storage Temperature: If you’ve dissolved a peptide in a solvent (e.g., water, acetic acid, or another buffer), you should store it at 2–8°C (36–46°F)
Protect from Light: Peptides in solution can degrade when exposed to light, so store them in amber-colored vials or protect them from light using foil or opaque containers.
Stability: Once reconstituted, peptides are typically stable for a few days to a few weeks at 4°C, depending on the sequence and conditions, but freezing is often the safest option for long-term storage.
3. Special Considerations:
Buffer Choice: Ensure the peptide is dissolved in an appropriate buffer to maintain stability. Some peptides may degrade in certain solvents, so it’s essential to choose the right one.
Avoid Contamination: Always handle peptides with clean equipment (e.g., sterile vials, pipettes) to prevent contamination that could affect their stability.
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Each unit is prepared with attention to consistency. Packaging is sealed and reinforced to protect shipment integrity. In addition, we offer Protection Coverage at checkout as an additional option which covers lost or damaged packages ($3.99). We’ll re-ship or refund eligible orders once confirmed. For additional information please visit our Shipping Policy and tracking Info Page
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Certificate of Analysis
View the Certificate of Analysis for this batch, provided by our testing lab.
Download COA (PDF)
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