$39.49Original price was: $39.49.$29.49Current price is: $29.49.
Sale Ends In:
Loading...
CJC NO DAC Modified GRF 1-29 5MG is formulated for precise research applications. At Ultra Peps, we prioritize consistency, reliability, and research-focused handling standards.
Growth hormone signaling investigations
IGF-1 pathway research
Trusted research supplier
Fast order processing
Reconstitution Required: This product recommends Reconstitution solution Add Reconstitution Solution
CJC No DAC Mod GRF 1-29 5mg is a synthetic analog of Growth Hormone Releasing Hormone (GHRH) designed to interact with GHRH receptors located within the anterior pituitary gland. Additionally, researchers study this peptide for its ability to influence endogenous growth hormone signaling and associated endocrine communication pathways.
Modified GRF 1-29, often referred to as Mod GRF (1-29), is structurally similar to naturally occurring GHRH but contains specific amino acid substitutions that improve stability while maintaining a short-acting activity profile.
Furthermore, researchers commonly utilize this compound in laboratory studies involving hormone regulation, receptor activation, growth factor signaling, and peptide pharmacology. As a result, Mod GRF (1-29) remains a valuable tool for investigating pulsatile endocrine signaling and receptor-mediated biological responses.
Mode of Action
Mod GRF (1-29) functions as a Growth Hormone Releasing Hormone (GHRH) analog that binds to GHRH receptors located on somatotroph cells within the anterior pituitary gland. Upon receptor binding, intracellular signaling pathways are activated, leading to the release of endogenous growth hormone from pituitary stores. As a result, the peptide enhances naturally occurring growth hormone signaling while preserving the physiological sequence of endocrine communication and feedback regulation.
Furthermore, the amino acid substitutions within Mod GRF (1-29) improve resistance to enzymatic degradation compared to native GHRH, thereby increasing peptide stability while maintaining a short duration of activity. Consequently, receptor activation occurs in a transient and pulsatile manner, closely resembling natural growth hormone release patterns. This signaling activity influences downstream pathways associated with insulin-like growth factor-1 (IGF-1), growth factor regulation, and endocrine communication networks.
No DAC vs DAC
No DAC = Natural, Pulsatile GH: Mimics the body’s natural rhythm, Less desensitization, Can be researched long-term.
With DAC = Sustained GH for days: GH elevation, Higher IGF-1
CJC 1295 with DAC also connects to GHRH receptor and growth hormone pathway research. Additionally, researchers may compare CJC 1295 with DAC and CJC No DAC MOD GRF 1-29 because one produces prolonged, sustained growth hormone elevation through albumin binding, while the other supports short-duration pulsatile signaling research.
Ipamorelin supports research involving growth hormone secretagogue pathways through ghrelin receptor activation. In simple terms, scientists may compare it with CJC No DAC MOD GRF 1-29 to study how two different receptor pathways can be examined together to model complementary growth hormone signaling activity.
Sermorelin closely relates to CJC No DAC MOD GRF 1-29 in research involving native GHRH sequence activity and anterior pituitary signaling. Therefore, researchers often examine these compounds when comparing structural differences between native and modified GHRH analog peptides.
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Peptides should be stored properly to maintain their stability and effectiveness. Here are some general guidelines for storing peptides:
1. Lyophilized (Dry/Powder) Peptides:
Storage Temperature: Store at -20°C or -80°C. Lyophilized peptides are typically more stable at lower temperatures.
Avoid Moisture: Keep them in airtight containers to avoid moisture exposure, which can degrade peptides.
Expiration: Lyophilized peptides generally have a longer shelf life when stored properly (up to a year or more).
2. Reconstituted Peptides (in Solution):
Storage Temperature: If you’ve dissolved a peptide in a solvent (e.g., water, acetic acid, or another buffer), you should store it at 2–8°C (36–46°F)
Protect from Light: Peptides in solution can degrade when exposed to light, so store them in amber-colored vials or protect them from light using foil or opaque containers.
Stability: Once reconstituted, peptides are typically stable for a few days to a few weeks at 4°C, depending on the sequence and conditions, but freezing is often the safest option for long-term storage.
3. Special Considerations:
Buffer Choice: Ensure the peptide is dissolved in an appropriate buffer to maintain stability. Some peptides may degrade in certain solvents, so it’s essential to choose the right one.
Avoid Contamination: Always handle peptides with clean equipment (e.g., sterile vials, pipettes) to prevent contamination that could affect their stability.
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Each unit is prepared with attention to consistency. Packaging is sealed and reinforced to protect shipment integrity. In addition, we offer Protection Coverage at checkout as an additional option which covers lost or damaged packages ($3.99). We’ll re-ship or refund eligible orders once confirmed. For additional information please visit our Shipping Policy and tracking Info Page
We ship USPS Priority only
Ships same day M-F (before 4pm est cutoff)
Orders placed on a Federal holiday or weekend will be delivered on the next business day
Free shipping on orders over $150. This offer will be available based on post-discount order amount
Signature confirmation is offered at checkout for $19.99
Yes, we ship to PO Boxes
Tracking & Insurance (up to $100 via USPS) is included
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
I. RESEARCH USE ONLY: Products are sold strictly for laboratory research and in-vitro testing, not for human or animal use. II. ASSUMPTION OF RISK: You assume all risk associated with these chemicals. III. LIABILITY: You agree to indemnify BCUltra LLC for any misuse, including human consumption. IV. COMPLIANCE: You certify you are 21+ & will handle these peptides & chems per all applicable law.
0 items
Order Before 4PM ET - Ships Same Day (Mon–Fri) Free Shipping on orders $150 +
New here? Take 10% off your first order with code WELCOME10 at checkout.
If you prefer to pay with credit card (Visa, Master Card, American Express, Discover) Apple Pay & Cash App, we now have that option available on our sister site: https://ultrapeptides.com/
We will be implementing this method of payment here shortly. Until then, Venmo and Crypto is still available. Thank you for your continued support and patience.
Order Before 4PM ET - Ships Same Day (Mon–Fri) 
Free Shipping on orders $150 +
CJC NO DAC MOD GRF 1-29 5mg
$39.49Original price was: $39.49.$29.49Current price is: $29.49.CJC NO DAC Modified GRF 1-29 5MG is formulated for precise research applications. At Ultra Peps, we prioritize consistency, reliability, and research-focused handling standards.
Description
CJC No DAC Mod GRF 1-29 5mg is a synthetic analog of Growth Hormone Releasing Hormone (GHRH) designed to interact with GHRH receptors located within the anterior pituitary gland. Additionally, researchers study this peptide for its ability to influence endogenous growth hormone signaling and associated endocrine communication pathways.
Modified GRF 1-29, often referred to as Mod GRF (1-29), is structurally similar to naturally occurring GHRH but contains specific amino acid substitutions that improve stability while maintaining a short-acting activity profile.
Furthermore, researchers commonly utilize this compound in laboratory studies involving hormone regulation, receptor activation, growth factor signaling, and peptide pharmacology. As a result, Mod GRF (1-29) remains a valuable tool for investigating pulsatile endocrine signaling and receptor-mediated biological responses.
Mode of Action
Mod GRF (1-29) functions as a Growth Hormone Releasing Hormone (GHRH) analog that binds to GHRH receptors located on somatotroph cells within the anterior pituitary gland. Upon receptor binding, intracellular signaling pathways are activated, leading to the release of endogenous growth hormone from pituitary stores. As a result, the peptide enhances naturally occurring growth hormone signaling while preserving the physiological sequence of endocrine communication and feedback regulation.
Furthermore, the amino acid substitutions within Mod GRF (1-29) improve resistance to enzymatic degradation compared to native GHRH, thereby increasing peptide stability while maintaining a short duration of activity. Consequently, receptor activation occurs in a transient and pulsatile manner, closely resembling natural growth hormone release patterns. This signaling activity influences downstream pathways associated with insulin-like growth factor-1 (IGF-1), growth factor regulation, and endocrine communication networks.
No DAC vs DAC
No DAC = Natural, Pulsatile GH: Mimics the body’s natural rhythm, Less desensitization, Can be researched long-term.
With DAC = Sustained GH for days: GH elevation, Higher IGF-1
Research Applications
This compound is commonly used in:
• Controlled laboratory analysis
• Growth hormone signaling investigations
• IGF-1 pathway research
• Endocrine communication studies
• GHRH receptor activity research
Related Research Compounds
CJC 1295 with DAC 5mg
CJC 1295 with DAC also connects to GHRH receptor and growth hormone pathway research. Additionally, researchers may compare CJC 1295 with DAC and CJC No DAC MOD GRF 1-29 because one produces prolonged, sustained growth hormone elevation through albumin binding, while the other supports short-duration pulsatile signaling research.
Ipamorelin 5mg
Ipamorelin supports research involving growth hormone secretagogue pathways through ghrelin receptor activation. In simple terms, scientists may compare it with CJC No DAC MOD GRF 1-29 to study how two different receptor pathways can be examined together to model complementary growth hormone signaling activity.
Sermorelin 2mg
Sermorelin closely relates to CJC No DAC MOD GRF 1-29 in research involving native GHRH sequence activity and anterior pituitary signaling. Therefore, researchers often examine these compounds when comparing structural differences between native and modified GHRH analog peptides.
Selected Literature
Read our Blog: CJC-1295 and GHRP-6: A Research-Focused Overview of Growth Hormone Pathway Signaling
Read our Blog: What Peptides Do in the Body: Understanding Their Role in Biological Research
Read our Blog: Understanding Peptide Half-Life in Research: Stability, Signaling, and Duration
https://en.wikipedia.org/wiki/Growth_hormone%E2%80%93releasing_hormone
Chemical Details
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Additional information
Solid (Powder)
White
5mg
peptide analogue of growth hormone-releasing hormone (GHRH)
Research Peptide
Ultra Peps
Peptides should be stored properly to maintain their stability and effectiveness. Here are some general guidelines for storing peptides:
1. Lyophilized (Dry/Powder) Peptides:
Storage Temperature: Store at -20°C or -80°C. Lyophilized peptides are typically more stable at lower temperatures.
Avoid Moisture: Keep them in airtight containers to avoid moisture exposure, which can degrade peptides.
Expiration: Lyophilized peptides generally have a longer shelf life when stored properly (up to a year or more).
2. Reconstituted Peptides (in Solution):
Storage Temperature: If you’ve dissolved a peptide in a solvent (e.g., water, acetic acid, or another buffer), you should store it at 2–8°C (36–46°F)
Protect from Light: Peptides in solution can degrade when exposed to light, so store them in amber-colored vials or protect them from light using foil or opaque containers.
Stability: Once reconstituted, peptides are typically stable for a few days to a few weeks at 4°C, depending on the sequence and conditions, but freezing is often the safest option for long-term storage.
3. Special Considerations:
Buffer Choice: Ensure the peptide is dissolved in an appropriate buffer to maintain stability. Some peptides may degrade in certain solvents, so it’s essential to choose the right one.
Avoid Contamination: Always handle peptides with clean equipment (e.g., sterile vials, pipettes) to prevent contamination that could affect their stability.
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Each unit is prepared with attention to consistency. Packaging is sealed and reinforced to protect shipment integrity. In addition, we offer Protection Coverage at checkout as an additional option which covers lost or damaged packages ($3.99). We’ll re-ship or refund eligible orders once confirmed. For additional information please visit our Shipping Policy and tracking Info Page
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Certificate of Analysis
View the Certificate of Analysis for this batch, provided by our testing lab.
Download COA (PDF)
You may also like…
GHRP 6 5mg
$17.99 – $69.99Price range: $17.99 through $69.99 Select options This product has multiple variants. The options may be chosen on the product pageGHRP 2 5mg
$17.99 – $69.99Price range: $17.99 through $69.99 Select options This product has multiple variants. The options may be chosen on the product pageCJC no DAC w/ Ipamorelin 5mg
$55.99 – $245.99Price range: $55.99 through $245.99 Select options This product has multiple variants. The options may be chosen on the product pageCJC 1295 NO DAC 5mg
$38.99 – $145.99Price range: $38.99 through $145.99 Select options This product has multiple variants. The options may be chosen on the product pageHexarelin 5mg
$33.49 Add to cartIpamorelin 5mg
$33.99 – $119.99Price range: $33.99 through $119.99 Select options This product has multiple variants. The options may be chosen on the product pageRelated products
IGF 1 LR3 1mg
$55.99 – $245.99Price range: $55.99 through $245.99 Select options This product has multiple variants. The options may be chosen on the product pageMelanotan 1 (MT-1) 10mg
$33.59Original price was: $33.59.$24.59Current price is: $24.59.DSIP (Delta Sleep Inducing Peptide) 5mg
$34.99 – $123.99Price range: $34.99 through $123.99 Select options This product has multiple variants. The options may be chosen on the product pageAICAR 50mg
$55.99 Add to cart