CJC 1295 with DAC (drug affinity complex) 5mg is formulated for precise research applications. At Ultra Peps, we prioritize consistency, reliability, and research-focused handling standards.
Growth hormone signaling investigations
Drug Affinity Complex (DAC) modification allows the peptide to extend its half-life and duration
Trusted research supplier
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Save when you purchase 5 *(coupon codes cannot be used in conjunction)
Reconstitution Required: This product recommends Reconstitution solution Add Reconstitution Solution
CJC-1295 with DAC 5mg is a synthetic growth hormone-releasing hormone (GHRH) analog designed to interact with GHRH receptors and influence growth hormone signaling pathways. Additionally, the inclusion of a Drug Affinity Complex (DAC) extends the peptide’s activity profile, allowing researchers to investigate prolonged receptor activation and sustained endocrine signaling.
Due to its extended half-life, CJC-1295 with DAC is frequently utilized in laboratory studies involving hormone regulation, growth factor signaling, receptor activity, and peptide pharmacology. Furthermore, researchers commonly use this compound to examine long-duration endocrine communication pathways and the biological effects associated with sustained receptor engagement. As a result, CJC-1295 with DAC remains a valuable research tool in endocrine and growth factor-related investigations.
Mode of Action
CJC with DAC is a combination of 2 peptides. It is a growth hormone releasing hormone (GHRH) that is studied for one side of the pituitary gland. It does this in order to produce growth hormone. GHRH comes from the hypothalamus. Its pulsatile release from the hypothalamus triggers a release of GH from the pituitary gland.
GHRH has a very short half-life of only a few minutes (half-life = the time required to remove half of the substance from the blood). For instance, the shorter the half-life, the more rapidly the substance disappears from the body, and the less its effect on the body.
In addition, the first 29 amino acids of GHRH is the active segment. They are available as a manufactured peptide called Sermorelin. Sermorelin increases its half-life to 30 minutes which is CJC 1295. CJC 1295 then added DAC (Drug Affinity Complex) to it. DAC binds to a blood protein called albumin, which increases its half-life to 8 days which is CJC 1295 + DAC.
Therefore, the longer half-life from the DAC binding to albumin means a relatively constant blood level provides a constant stimulus for GH release from the pituitary through the GHRH receptor, which is not physiological. In short, This can decrease the GH pulse amplitude which will result in decreased GH tissue stimulation.
Short-acting (30 minutes), Researched for GH pulses, not sustained elevation, Often paired with Ipamorelin, “CJC No DAC” = natural GH rhythm enhancer, “CJC With DAC” = long GH elevation. If you want the closest version without the long half-life, this is it.
CJC-1295 with DAC / Tetrasubstituted GRF(1-29) with Drug Affinity Complex
Molecular Formula
C165H269N47O46
Molecular Weight
3647.30 g/mol
Sequence
Modified GHRH(1-29) with a DAC conjugation group
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Peptides should be stored properly to maintain their stability and effectiveness. Here are some general guidelines for storing peptides:
1. Lyophilized (Dry/Powder) Peptides:
Storage Temperature: Store at -20°C or -80°C. Lyophilized peptides are typically more stable at lower temperatures.
Avoid Moisture: Keep them in airtight containers to avoid moisture exposure, which can degrade peptides.
Expiration: Lyophilized peptides generally have a longer shelf life when stored properly (up to a year or more).
2. Reconstituted Peptides (in Solution):
Storage Temperature: If you’ve dissolved a peptide in a solvent (e.g., water, acetic acid, or another buffer), you should store it at 2–8°C (36–46°F)
Protect from Light: Peptides in solution can degrade when exposed to light, so store them in amber-colored vials or protect them from light using foil or opaque containers.
Stability: Once reconstituted, peptides are typically stable for a few days to a few weeks at 4°C, depending on the sequence and conditions, but freezing is often the safest option for long-term storage.
3. Special Considerations:
Buffer Choice: Ensure the peptide is dissolved in an appropriate buffer to maintain stability. Some peptides may degrade in certain solvents, so it’s essential to choose the right one.
Avoid Contamination: Always handle peptides with clean equipment (e.g., sterile vials, pipettes) to prevent contamination that could affect their stability.
Property
Value
Chemical Name
CJC-1295 with DAC / Tetrasubstituted GRF(1-29) with Drug Affinity Complex
Molecular Formula
C165H269N47O46
Molecular Weight
3647.30 g/mol
Sequence
Modified GHRH(1-29) with a DAC conjugation group
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Each unit is prepared with attention to consistency. Packaging is sealed and reinforced to protect shipment integrity. In addition, we offer Protection Coverage at checkout as an additional option which covers lost or damaged packages ($3.99). We’ll re-ship or refund eligible orders once confirmed. For additional information please visit our Shipping Policy and tracking Info Page
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Ships same day M-F (before 4pm est cutoff)
Orders placed on a Federal holiday or weekend will be delivered on the next business day
Free shipping on orders over $150. This offer will be available based on post-discount order amount
Signature confirmation is offered at checkout for $19.99
Yes, we ship to PO Boxes
Tracking & Insurance (up to $100 via USPS) is included
Property
Value
Chemical Name
CJC-1295 with DAC / Tetrasubstituted GRF(1-29) with Drug Affinity Complex
Molecular Formula
C165H269N47O46
Molecular Weight
3647.30 g/mol
Sequence
Modified GHRH(1-29) with a DAC conjugation group
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
I. RESEARCH USE ONLY: Products are sold strictly for laboratory research and in-vitro testing, not for human or animal use. II. ASSUMPTION OF RISK: You assume all risk associated with these chemicals. III. LIABILITY: You agree to indemnify BCUltra LLC for any misuse, including human consumption. IV. COMPLIANCE: You certify you are 21+ & will handle these peptides & chems per all applicable law.
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CJC 1295 with DAC 5mg
$44.99 – $189.99Price range: $44.99 through $189.99
CJC 1295 with DAC (drug affinity complex) 5mg is formulated for precise research applications. At Ultra Peps, we prioritize consistency, reliability, and research-focused handling standards.
Description
CJC-1295 with DAC 5mg is a synthetic growth hormone-releasing hormone (GHRH) analog designed to interact with GHRH receptors and influence growth hormone signaling pathways. Additionally, the inclusion of a Drug Affinity Complex (DAC) extends the peptide’s activity profile, allowing researchers to investigate prolonged receptor activation and sustained endocrine signaling.
Due to its extended half-life, CJC-1295 with DAC is frequently utilized in laboratory studies involving hormone regulation, growth factor signaling, receptor activity, and peptide pharmacology. Furthermore, researchers commonly use this compound to examine long-duration endocrine communication pathways and the biological effects associated with sustained receptor engagement. As a result, CJC-1295 with DAC remains a valuable research tool in endocrine and growth factor-related investigations.
Mode of Action
CJC with DAC is a combination of 2 peptides. It is a growth hormone releasing hormone (GHRH) that is studied for one side of the pituitary gland. It does this in order to produce growth hormone. GHRH comes from the hypothalamus. Its pulsatile release from the hypothalamus triggers a release of GH from the pituitary gland.
GHRH has a very short half-life of only a few minutes (half-life = the time required to remove half of the substance from the blood). For instance, the shorter the half-life, the more rapidly the substance disappears from the body, and the less its effect on the body.
In addition, the first 29 amino acids of GHRH is the active segment. They are available as a manufactured peptide called Sermorelin. Sermorelin increases its half-life to 30 minutes which is CJC 1295. CJC 1295 then added DAC (Drug Affinity Complex) to it. DAC binds to a blood protein called albumin, which increases its half-life to 8 days which is CJC 1295 + DAC.
Therefore, the longer half-life from the DAC binding to albumin means a relatively constant blood level provides a constant stimulus for GH release from the pituitary through the GHRH receptor, which is not physiological. In short, This can decrease the GH pulse amplitude which will result in decreased GH tissue stimulation.
Research Applications
This compound is commonly used in:
• Controlled laboratory analysis
• Growth hormone signaling investigations
• IGF-1 pathway research
• Endocrine communication studies
• GHRH receptor activity research
Related Research Compounds
1. MOD GRF 1-29 (a.k.a. CJC-1295 No DAC)
Short-acting (30 minutes), Researched for GH pulses, not sustained elevation, Often paired with Ipamorelin, “CJC No DAC” = natural GH rhythm enhancer, “CJC With DAC” = long GH elevation. If you want the closest version without the long half-life, this is it.
2. Tesamorelin
Strong GHRH analog, Clinically stronger than CJC, Increase in IGF-1, Considered a more powerful pharmaceutical version.
3. Sermorelin
Very similar to CJC (No DAC), Shorter acting, Good for long-term GH/IGF-1 research, Not as strong as CJC w/DAC but very close in mechanism.
Peptides Functionally Similar (GH Secretagogues)
These don’t work exactly the same but produce similar outcomes
4. Ipamorelin
GH secretagogue, Often researched with CJC-1295, Great synergy with No DAC version, Similar outcome but different receptor (GHSR).
5. GHRP-2
Strong GH releaser, Works well with CJC peptides, Stronger but less clean than Ipamorelin
6. GHRP-6
Very potent GH releaser, Similar GH effects to CJC but on different pathway.
7. Hexarelin
The strongest GH secretagogue, Produces significant GH spikes, Desensitizes faster.
Selected Literature
Read our Blog: CJC-1295 and GHRP-6: A Research-Focused Overview of Growth Hormone Pathway Signaling
Read our Blog: What Peptides Do in the Body: Understanding Their Role in Biological Research
Read our Blog: Understanding Peptide Half-Life in Research: Stability, Signaling, and Duration
https://en.wikipedia.org/wiki/Growth_hormone%E2%80%93releasing_hormone
Chemical Details
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Additional information
Solid (Powder)
White
5mg
peptide analogue of growth hormone-releasing hormone (GHRH)
Research Peptide
Ultra Peps
1, 5
Peptides should be stored properly to maintain their stability and effectiveness. Here are some general guidelines for storing peptides:
1. Lyophilized (Dry/Powder) Peptides:
Storage Temperature: Store at -20°C or -80°C. Lyophilized peptides are typically more stable at lower temperatures.
Avoid Moisture: Keep them in airtight containers to avoid moisture exposure, which can degrade peptides.
Expiration: Lyophilized peptides generally have a longer shelf life when stored properly (up to a year or more).
2. Reconstituted Peptides (in Solution):
Storage Temperature: If you’ve dissolved a peptide in a solvent (e.g., water, acetic acid, or another buffer), you should store it at 2–8°C (36–46°F)
Protect from Light: Peptides in solution can degrade when exposed to light, so store them in amber-colored vials or protect them from light using foil or opaque containers.
Stability: Once reconstituted, peptides are typically stable for a few days to a few weeks at 4°C, depending on the sequence and conditions, but freezing is often the safest option for long-term storage.
3. Special Considerations:
Buffer Choice: Ensure the peptide is dissolved in an appropriate buffer to maintain stability. Some peptides may degrade in certain solvents, so it’s essential to choose the right one.
Avoid Contamination: Always handle peptides with clean equipment (e.g., sterile vials, pipettes) to prevent contamination that could affect their stability.
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Each unit is prepared with attention to consistency. Packaging is sealed and reinforced to protect shipment integrity. In addition, we offer Protection Coverage at checkout as an additional option which covers lost or damaged packages ($3.99). We’ll re-ship or refund eligible orders once confirmed. For additional information please visit our Shipping Policy and tracking Info Page
THIS PRODUCT IS FOR RESEARCH ONLY
This designation allows the use of research chemicals and peptides strictly for in vitro testing and research. It is to be handled by qualified and licensed professionals, in laboratory settings only.
Bodily introduction of any kind, into humans or animals, is strictly illegal by law.This product is NOT for human use and can be harmful if ingested. This product is not in a sterile solution. It is not a drug, food, or cosmetic.
Please read our Terms and Conditions prior to ordering.
Certificate of Analysis
View the Certificate of Analysis for this batch, provided by our testing lab.
Download COA (PDF)
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